SMPlayer 使用屢獲殊榮的 MPlayer 作為播放引擎，它能夠使用內建的解碼器播放幾乎所有的視訊和音訊格式。
在這裡您可以看到一份支援格式和解碼器的清單。
| (S)VCD (Super Video CD) |
| CDRwin's .bin image file |
| DVD, including encrypted DVD |
| MPEG-1/2 (ES/PS/PES/VOB) |
| AVI file format |
| ASF/WMV/WMA format |
| QT/MOV/MP4 format |
| RealAudio/RealVideo format |
| Ogg/OGM files |
| Matroska |
| NUT |
| NSV (Nullsoft Streaming Video) |
| VIVO format |
| FLI format |
| NuppelVideo format |
| yuv4mpeg format |
| FILM (.cpk) format |
| RoQ format |
| PVA format |
| streaming via HTTP/FTP, RTP/RTSP, MMS/MMST, MPST, SDP |
| TV grabbing |
| MPEG-1 (VCD) and MPEG-2 (SVCD/DVD/DVB) video |
| MPEG-4 ASP in all variants including DivX ;-), OpenDivX (DivX4), DivX 5 (Pro), Xvid |
| MPEG-4 AVC aka H.264 |
| Windows Media Video 7/8 (WMV1/2) |
| Windows Media Video 9 (WMV3) (using x86 DLL) |
| RealVideo 1.0, 2.0 (G2) |
| RealVideo 3.0 (RP8), 4.0 (RP9) (using Real libraries) |
| Sorenson v1/v3 (SVQ1/SVQ3), Cinepak, RPZA and other QuickTime codecs |
| DV video |
| 3ivx |
| Intel Indeo3 (3.1, 3.2) |
| Intel Indeo 4.1 and 5.0 (using x86 DLL or XAnim codecs) |
| VIVO 1.0, 2.0, I263 and other H.263(+) variants (using x86 DLL) |
| MJPEG, AVID, VCR2, ASV2 and other hardware formats |
| FLI/FLC |
| HuffYUV |
| various old simple RLE-like formats |
| MPEG layer 1, 2, and 3 (MP3) audio |
| AC3/A52, E-AC3, DTS (Dolby Digital) audio (software or SP/DIF) |
| AAC (MPEG-4 audio) |
| WMA (DivX Audio) v1, v2 |
| WMA 9 (WMAv3), Voxware audio, ACELP.net etc (using x86 DLLs) |
| RealAudio: COOK, SIPRO, ATRAC3 (using Real libraries) |
| RealAudio: DNET and older codecs |
| QuickTime: Qclp, Q-Design QDMC/QDM2, MACE 3/6 (using QT libraries), ALAC |
| Ogg Vorbis audio |
| VIVO audio (g723, Vivo Siren) (using x86 DLL) |
| alaw/ulaw, (ms)gsm, pcm, *adpcm and other simple old audio formats |